For fever, which is better ibuprofen or nurofen for a child?

The drug Ibuklin for children. Instructions for use

Expert: Zalman Rivlin
Ibuklin and Paracetamol are drugs from the NSAID group. Nonsteroidal anti-inflammatory drugs reduce body temperature, relieve pain, reduce inflammation and alleviate general condition. They are prescribed to adults and children, and are used during pregnancy and lactation. It is unlikely that among those reading this article there will be a person who has not heard about these drugs. Want to know the difference between them?

Experts from our magazine conducted a comparative analysis of antipyretic drugs and found out how Paracetamol differs from Ibuklin. We learned that Ibuklin is a combination drug. It contains the same paracetamol and ibuprofen. This combination relieves fever and pain faster and more effectively, but is also more likely to cause serious adverse reactions.

The final choice of drug will depend on the specific clinical situation. In some cases, you cannot do without Ibuklin, in others you can limit yourself to simple Paracetamol. We won’t reveal all our cards – read the article for details.

Indications for use, instructions for use

What can Ibuklin tablets help with? This medicine is in a leading position among the countless number of anti-inflammatory drugs offered today in pharmacies in Minsk and other cities.

When and why does a doctor prescribe Ibuklin for children? For children, the medicine is indicated to relieve pain of any kind. Indications for the use of the drug "Ibuklin for children" are headaches, sore throats, injuries, bruises and sprains.

In addition, the annotation for the drug states that it can be used by children during toothache, sore throat, chickenpox, and also during teething. It can be given to children of any age, even if they are still breastfed.

Medicines “Ibuklin Children” and “Ibuklin Junior” are drugs for acute viral diseases and colds, providing symptomatic therapy, reducing the intensity of inflammation and reducing pathological symptoms. From what age can you take this medicine? From the age of three months, even for nursing mothers or women in the last trimester of pregnancy.

"Ibuklin" is also prescribed to children for certain ENT diseases, such as otitis, sinusitis, pharyngitis, tonsillitis, laryngitis. Adults can also take the medicine "Ibuklin". The annotation in the picture for adults states that the medicine should be taken for the same pathological conditions, that is, during acute respiratory viral infections, inflammatory processes in the respiratory organs of any kind, painful menstruation, migraines and other conditions that are accompanied by unbearable pain or high fever. Pregnant women and during breastfeeding should take the medicine with caution, i.e. lactation. You should avoid taking the medicine completely if the adult drinks alcohol that day. In this case, it is better to use it as a substitute for a candle or ointment. Although the effect is different.

Is the medicine “Ibuklin Children” an antibiotic?

Due to the fact that this medicine is prescribed for colds and acute respiratory viral infections, some are concerned with the following question: “Is the medicine Ibuklin an antibiotic?” This drug contains two components:

Paracetamol, which has antipyretic and anti-inflammatory effects, as well as a pronounced analgesic effect.

Ibuprofen, which is a non-hormonal anti-inflammatory drug that relieves pain symptoms, lowers temperature during fever, menstruation and reduces the intensity of inflammatory processes.

The high effectiveness of the drug "Ibuklin Children" can be explained to the mother by the combination of these two different drugs, which belong to the same drug group. On the packaging there is an opinion of experts that the use of ibuprofen and paracetamol separately is not able to demonstrate such pronounced results. Wikipedia also notes the compatibility of these drugs and their remarkable properties.

clearly gives a negative answer: “No!” The drug does not have the slightest effect on pathogenic microorganisms. Indications for use are exclusively symptomatic therapy, which helps alleviate the well-being of patients with various diseases. Can be used in complex therapy with antiviral and antibacterial drugs, as well as together with a noshpa.

The dosage is written in the recipe. How much to take the medicine, how long it takes for it to start working, these questions will be answered by the attending physician when writing a prescription. After taking it, the patient already looks much better after ten minutes than before.

Which is better - Ibuprofen or Ibuclin?

Ibuklin is considered the most popular drug for symptomatic treatment for both adults and children. The drug is most effective, has a minimum number of contraindications and is well tolerated by the child’s body. But the opinion of experts is clear: “Ibuklin for children” is much better.” And no other medicinal analogues that are glorified by advertising, such as Kagocel, Nurofen, Amoxilav, Ingaverin, Amoxilav, Ibufen (the list can be very long) can replace it. Plus it's cheaper. The cost of promotional tablets, capsules and suspensions is higher. It turns out the difference is noticeable.

Body temperature is often one of the signs indicating the development of some pathological conditions. An increase in thermometer readings in most cases indicates that the human body has defended itself against the invasion of viral or bacterial infections. And in order not to disturb him, you should not lower the temperature until it reaches significant numbers (there are exceptions). In order to cope with elevated temperatures, various medicinal formulations can be used.

Paracetamol

This drug has an analgesic and antipyretic effect; it belongs to non-steroidal anti-inflammatory drugs. The active substance of this medication is called paracetamol and is a derivative of phenacetin.

On sale there are tablets intended for oral consumption (two hundred and five hundred milligrams), capsules (five hundred milligrams), and special effervescent formulations used to make a solution (five hundred milligrams). You can purchase Paracetamol in the form of a solution for infusion (one milliliter contains fifteen milligrams of the active substance, and one ampoule contains five milliliters), as a children's syrup (five milliliters contains two hundred milligrams of paracetamol). The drug is also available in the form of a children's suspension (five milliliters - one hundred and twenty milligrams of the active substance), and as rectal suppositories with different dosages (from fifty to a thousand milligrams).

A single dosage of this medication can range from five hundred to a thousand milligrams for adults and adolescents over twelve years of age. In this case, the daily amount of paracetamol consumed should not exceed four grams. As for the use of this medicine in childhood, the calculation of the recommended dosage is carried out exclusively individually, in accordance with the weight of the baby. The dose can range from one hundred twenty-five to two hundred and fifty milligrams at a time. The daily amount should be distributed into four doses with an equal interval between consumption (at least four hours).

You should not use paracetamol for more than three days in a row without consulting a doctor.

The drug should not be used in case of hypersensitivity, problems with the kidneys and liver, impaired blood count, during pregnancy and lactation.

Ibuklin

This medicinal composition acts as an antipyretic and also eliminates pain and inflammatory processes. The drug contains ibuprofen and paracetamol. Its main advantage is a longer-lasting effect than from taking ibuprofen or paracetamol alone.

This composition can be purchased in two different forms, as tablets for children and for adults. Children's Ibuklin contains one hundred milligrams of ibuprofen and one hundred twenty-five milligrams of paracetamol. An adult can take four hundred milligrams of ibuprofen, as well as three hundred and twenty-five milligrams of paracetamol.

Tablets for fever with paracetamol Ibuklin cannot be used for problems with the liver, disturbances in the functioning of the hematopoietic organs, hypersensitivity, or the presence of erosive and ulcerative lesions of the digestive tract (during exacerbations). You should not take Ibuklin if you are intolerant to acetylsalicylic acid, have diseases of the optic nerve, or lack an enzyme such as glucose-6-phosphate dehydrogenase. Contraindications also include pregnancy and breastfeeding.

Adults and adolescents over twelve years of age are prescribed one or two tablets of the medicine two to three times a day. The maximum daily dosage is six tablets. In childhood, the daily dose is calculated depending on weight. Per kilogram of body weight, you can consume no more than twenty milligrams of the drug, this amount is divided into several doses.

Nurofen

This medicine contains ibuprofen, which is a derivative derived from phenylpropionic acid. Many researchers claim that this medicinal composition also has an immunostimulating effect, due to the fact that it activates the body’s production of its own interferon.

Nurofen can be purchased as sugar-coated tablets (each containing two hundred milligrams of the substance), as well as in the form of effervescent tablets (two hundred milligrams of ibuprofen), rectal suppositories (sixty milligrams of the active ingredient) and a special children's suspension with pleasant flavors (strawberry or orange ) (five milliliters - one hundred milligrams of ibuprofen).

Tablets for fever with paracetamol Nurofen should not be taken for inflammation of the digestive tract, blood diseases, aspirin triad, hypersensitivity, hypertension, kidney and liver problems, middle ear pathology, ophthalmological diseases, in children under three months of age, during lactation and in the third trimester of pregnancy .

Patients over twelve years of age can take up to one thousand two hundred milligrams of ibuprofen per day, dividing this amount into three to four doses. The maximum single dose is four hundred milligrams. From six to twelve years old, use a maximum of nine hundred milligrams per day. For younger children, the dosage is calculated depending on weight. You can take a maximum of thirty milligrams of ibuprofen per kilogram of body weight per day.

If a high temperature of unknown etiology appears or if the temperature rises in children, consult a doctor.

Among pharmacological drugs, non-steroidal anti-inflammatory drugs (NSAIDs) include a fairly large group of drugs. The mechanism of functioning of these chemicals is quite complex, but well studied. Describing the method of action in a few words, we note that when an inflammatory process arises in the body, special substances begin to be produced - prostaglandids, which affect the symptoms of the disease. In turn, NSAIDs are designed to reduce the severity of the inflammatory process.

The medicinal substances of this group are characterized by three main pharmacological effects:

1. anti-inflammatory;
2. analgesic;
3. antipyretic.

Of the variety of NSAIDs, let us compare the drugs Ibuklin and Ibuprofen, which are widely used as medicines for independent use.

Recommendations and interaction

Ibuklin Junior is able to mask the symptoms of infectious diseases. Therefore, only a doctor who has established an accurate diagnosis of the child’s pathology can prescribe it. The use of the drug is advisable in cases of severe febrile syndrome, as well as the patient’s ability to tolerate it. Simultaneous use of Ibuklin Junior with indirect anticoagulants requires constant monitoring of blood clotting indicators. It is prohibited to combine the drug with other NSAIDs. The drug can have a negative effect on the gastrointestinal tract, and therefore it is recommended to use the minimum amount of the drug that can produce a therapeutic effect in a short course.

Due to the fact that Ibuklin Junior is capable of distorting research results (quantitative determination of glucose, uric acid in blood serum and 17-ketosteroids), it is canceled two days before these tests.

If the patient takes the medicine for more than 5 days, which are recommended by experts, then it is necessary to check the condition of the liver, as well as peripheral blood.

Peculiarities of action with other drugs:

• Paracetamol: increased nephrotoxic effect;
• Glucocorticosteroids, ethanol, corticotropin: the likelihood of erosive and ulcerative lesions of the gastrointestinal tract increases;
• Anticoagulants, thrombolytic agents, colchicine: hemorrhagic complications;
• Insulin, oral glycemic drugs: increased glycemic effect;
• Diuretics and antihypertensive substances: decreased effect;
• Digoxin, lithium preparations, methotrexate: their concentration in the blood increases;
• Caffeine: increases the analgesic effect;
• Cyclosporine: nephrotoxicity;
• Antacids, cholestyramine: absorption of the substance decreases;
• Cefamandole, cefotetan, valproic acid, plicamycin: hypoprothrombinemia may develop.

Instructions for use

The instructions for use indicate that Ibuklin Junior is taken orally, after dissolving the tablet in 5 ml (teaspoon) of water. The interval between taking tablets should be at least 4 hours, and in case of impaired renal or liver function - at least 8 hours. It is recommended to divide the daily dose into 2-3 doses.

• 3–6 years with body weight 13–20 kg: 3 tablets;
• 6–12 years old with a body weight of 20–40 kg: up to 6 tablets.

The drug should not be taken for more than 5 days as an analgesic and for more than 3 days as an antipyretic without medical supervision.

How long does it take to work?

The immediate effect (10 minutes after taking the drug) is ensured by the high absorption of the active ingredients. The maximum concentration in the blood of Paracetamol is achieved after half an hour, and Ibuprofen - after 2 hours, so the rapid effect of the drug occurs thanks to Paracetamol, and the duration of action is ensured by Ibuprofen.

This substance tends to bind to blood plasma proteins and accumulate in the joint cavity, excreted mainly by the kidneys and a small part in the form of metabolites by the liver. The pharmacokinetics of paracetamol is characterized by:

• uniform distribution of the substance in the blood without providing a connection with protein;
• excretion by the kidneys;
• the ability to bind to the liver enzyme glutathione and block it in case of overdose, which can lead to necrosis.

Comparison of Ibuprofen and Nurofen

Nurofen is an analogue of Ibuprofen. Medicines have a number of similarities and differences.

Similarities

1. Mechanism of action. They have a rapid analgesic and anti-inflammatory effect and help lower body temperature.
2. They dissolve well and quickly enter the bloodstream. When taken on an empty stomach, their maximum concentration is observed after 45 minutes - 1 hour, after eating - after 1.5-2 hours.
3. The active substance has the same indications and contraindications.

What is the difference?

1. Various release forms. If Ibuprofen is available only in tablets, then Nurofen can be purchased in the form of capsules, suspensions, suppositories and gel. This is convenient for all patient groups.
2. Nurofen has forms that have higher bioavailability - they dissolve faster and have an analgesic effect within 15 minutes after administration.
3. Various manufacturers. Nurofen is produced by a European company, Ibuprofen is produced by a domestic company.
4. Nurofen has an extensive evidence base, its effectiveness has been confirmed by numerous clinical studies.
5. Due to the different excipients included in the drugs, they differ in the severity and frequency of side effects: when taking Nurofen there are much fewer of them.

What is more effective?

200 mg of Ibuprofen is equivalent in effectiveness to 200 mg of Nurofen. But this only applies to tablets. If you compare Ibuprofen tablets with capsules or a suspension of the second drug, the effect will be worse. The analgesic and antipyretic effect of liquid forms of Nurofen will occur faster, approximately 15-20 minutes after administration.

What's stronger?

The strength of the medicine depends on its dose. Depending on the severity of symptoms, it can be increased, the main thing is not to exceed the maximum daily dose of 1200 mg. To obtain this dosage, you need to take 6 tablets of ibuprofen per day, and Nurofen Forte only needs 3 tablets per day - due to the double dose of the active substance, it is stronger.

What is the difference between Ibuprofen and Nurofen?

The development of the pharmaceutical industry is rapidly filling pharmacies with the latest painkillers. The more well-known and accessible among them are Ibuprofen and Nurofen. Chemically similar in composition and action, these two products make buyers wonder which is more effective.

Ibuprofen and Nurofen are non-selective non-steroidal anti-inflammatory drugs that eliminate pain and have antipyretic properties. The action of medications is based on a laboratory substance called Ibuprofen.

Factory-made Ibuprofen of the same name is presented in pharmacy chains in the form of tablets with a dose of 200 mg.

Nurofen is the same as Ibuprofen, with medicinal additives and a variety of dosage forms of production, adapted for different age categories.

Both drugs perform the same pharmacological function, but in addition to the release options, there are some differences. For example, Ibuprofen is contraindicated in children under 16 years of age, while Nurofen is considered the best assistant in the fight against illnesses in children. The line of this painkiller is presented in the form of syrups, suspension solutions and rectal suppositories for children from 3 months to 12 years; for adolescents, tablets with a dose of 200 mg, 400 mg, 600 mg or 800 mg (from 6 years) and a gel for external use will be a convenient form of administration. applications. Another type of medication is codeine-containing Nurofen Plus, which helps reduce the excitability of the cough center.

Ibuprofen is presented as a pure film-coated tablet substance in 200 mg and 400 mg.

The similarity of drugs is determined by their side effects, indications and contraindications for use.

Indications for use are:

• Pain syndrome of moderate intensity (toothache, headache, migraine; damage to peripheral nerves - neuralgia, ear pain, throat pain and pain due to ligament injuries; muscle pain and joint pain; rheumatism, etc.
• Antipyretic for acute respiratory infections and influenza (infectious and inflammatory diseases and post-vaccination reactions, manifested by increased body temperature.

Contraindications are:

• cardiac diseases;
• individual intolerance to individual components;
• renal failure;
• hypertension;
• last trimester of pregnancy and lactation period;
• severe gastritis or bleeding, perforation of a gastrointestinal ulcer.

Side effects can be minimized if the drugs are used in a short cycle, in a moderate effective dose required for treatment. However, you should be prepared for them:

• nausea, abdominal pain, dyspepsia;
• nonspecific allergic reactions;
• bronchospasm and shortness of breath;
• emotional overload.

It is important to note that Nurofen is an imported Ibuprofen, patented as a trade name at the end of the last century in the UK.

Pharmaceutical production of European drugs undergoes multiple checks for compliance with certificates and quality control. Consequently, trust and price will be higher in contrast to domestic painkillers.

Ibuprofen tablets are produced in Poland, Belarus, Estonia and Russia. As patients note, the pharmacological dynamics and action do not differ from the effect of the foreign analogue and its cost is significantly lower.

Around medicines, disputes often increase among those who take and prescribe them regarding their effectiveness. However, even the best specialist will not easily prescribe a drug that will definitely alleviate the disease. The effectiveness of any medication or its analogues is determined by the individual susceptibility of the body. That is why Ibuprofen helps one person faster, while Nurofen has a stronger effect on another.

It turns out that everyone chooses the best medicine for themselves. However, in the fight against childhood infections and their accompanying manifestations, many pediatricians give priority to Nurofen. It is safe for the child and has several options for administration if the question of whimsicality arises. Smoothly copes with increased fever, as well as various pains, in the approximate period of time stated in the instructions.

The variety of pharmacodynamic effects of the group of non-steroidal anti-inflammatory drugs, to which both of our drugs belong, makes it possible to use them in different clinical situations, including neutropenia. To resolve this issue, the medical community recommends adding Ibuprofen to the treatment of such fungal diseases. In complex therapy for children, doctors give preference to it, introducing up to several tablets per day.

Basically, expert reviews of these medications are positive. Referring to compliance with the instructions, doctors also advise seeking qualified medical help.

Mikhail, pediatric neurologist, 50 years old, Arkhangelsk: “I prescribe Nurofen for children from 3 years old. I consider the use of Ibuprofen syrup to be environmentally friendly for the treatment of preschool children.”

Svetlana, dermatovenerologist, 39, Naberezhnye Chelny: “I use Russian Ibuprofen personally and in medical practice. Quite effective and long-lasting effect.”

Alexey, pediatrician, 44 years old, Moscow: “I prescribe Nurofen children’s suspension for children over 1 year of age with a high temperature, I recommend Ibuprofen for children over 9 years old.”

Victoria, mother, 30 years old, Volgograd: “Nurofen is really more effective in heat/temperature than its analogue ibuprofen. I'm talking about syrups now. After Nurofen, the temperature began to subside faster and the effect lasted longer. Now five hours have passed since the appointment and the child’s temperature is 36.6°C. She sleeps peacefully now.” Liliya, mother, 38 years old, Moscow: “Better is ibuprofen without additives and dyes. The effect is the same, there are fewer impurities"

Natalya, mother, 34 years old, Tyumen: “In this case, it’s the same thing, but it’s made from different raw materials. Different methods, degrees of purification and processing. As painkillers, they have the same effect. Nurafen is more effective as an antipyretic.”

Action of the medication

The combined drug "Ibuklin", the composition of which is described above, has an analgesic, antipyretic and anti-inflammatory effect due to the ibuprofen it contains. This component inhibits cyclooxygenase-1 and 2 (COX), disrupting the metabolism of omega-6-unsaturated fatty acid (arachidonic acid), reducing the amount of prostaglandins, suppressing the exudative phase of inflammation.

The action of paracetamol is aimed at blocking COX primarily in the central nervous system; in addition, this component has little effect on the gastrointestinal mucosa and the totality of the processes of entry of water and salts into the body. Has analgesic and antipyretic effects. The presence of peroxidase in inflamed tissues paralyzes the effect of paracetamol on COX-1 and COX-2, as a result of which the anti-inflammatory effect is greatly reduced.

The effectiveness of the combined drug is many times higher than that of the individual components present in it.

Product Features

Millet porridge has been present in Russian cooking for several centuries. The cereal was highly valued in Rus', called “golden grains,” not only because of its color, but also because the area under which it was sown was limited and was significantly inferior to wheat. The benefits of millet porridge with milk were well known to common and working people. Ideally digestible, this cereal provided a long-lasting feeling of satiety and helped restore strength.

However, the cereal did not go further than the southern regions of Russia. And not because climatic conditions did not allow. The point is in its characteristics, which almost completely excluded its use in the cooking of the northern regions. And in a modern kitchen there is only a limited place for “golden grains”.

The reason for this is several myths that have developed about millet porridge.

• The cereal is bitter . A common opinion is based on violation of the rules for its storage. Millet contains a huge amount of fatty acids. It is known how beneficial they are for the body. They participate in metabolic processes, ensure youthfulness of tissues and skin. A person can get these acids only from food, and millet porridge becomes an excellent source of them. However, if storage conditions are violated or stored for a long time, the fats in the grains oxidize and the cereal goes rancid. It is impossible to consume this, it really becomes unpleasant to the taste and loses its benefits.
• It is impossible to remove the bitterness . Another erroneous opinion. If the cereal has not expired, the bitterness can be easily removed by proper washing. It is carried out in three stages. First, the grains are rinsed from dust by washing in several waters. Then wash in hot water. This is enough for fresh millet, but not for slightly stale millet. This should be placed in a sieve and pour boiling water over it. It will wash away the greasy, rancid film, and the cereal will taste perfect again.
• There are few useful substances in cereals . The beneficial properties of millet porridge largely depend on the grain processing technique. The most useful thing is the drapes. It is distinguished by a dark, brown color, which is formed by the fruit shells. During production, only their upper part is removed, and the main part, which includes maximum fiber, is stored on the kernels. Dranets is especially capricious in storage; it goes rancid faster than other types of cereals. It is impossible to remove the bitterness, since when washed, rancid fats remain on the kernels. The choice of dranet should be based only on its freshness. Then you can get the maximum benefit from millet porridge. Polished grains contain less fiber, but there are enough other useful components, so you can and should use them in a healthy diet.
• Millet porridge is only suitable for baby food . Wrong judgment again. In Rus', peasants consumed it en masse, knowing about the ability of cereal to quickly restore strength. The reason for this is the ease with which cereal is absorbed in the body. It can be used by children and people with gastrointestinal diseases and metabolic disorders. For a healthy adult, millet porridge will be a useful and easily accessible source of energy, especially when engaged in heavy physical labor.

Selection and storage

Based on the above facts, we can give several recommendations for selecting and storing cereals.

Comparison

Ibuklin is a medicine that contains two active substances: paracetamol and ibuprofen.

• Paracetamol is an analgesic and antipyretic. It weakens the excitability of the thermoregulation center, resulting in a decrease in temperature;
• Ibuprofen is a non-steroidal anti-inflammatory drug that inhibits the synthesis of prostaglandins, which cause inflammation and pain. In addition, ibuprofen stimulates the production of interferon, which helps the body cope with viruses.

Ibuklin is released in 2 forms:

• Coated tablets for adults. Contains paracetamol 325 mg, ibuprofen 400 mg.
• Ibuklin junior. Tablets, easily soluble in water, for children from 3 years of age. Contains 125 mg paracetamol and 100 mg ibuprofen.

The medicine reduces temperature, eliminates fever and pain.

What is the difference between Ibuklin and Nurofen? The difference is actually in the composition, if the first drug contains 2 substances at once, then Nurofen consists of only one, namely ibuprofen. But there is a type of drug called Nurofen Long containing the same substances as Ibuklin. It contains paracetamol 500 mg and ibuprofen 200 mg. And also Nurofen plus, consisting of ibuprofen and codeine, which is a strong pain reliever. But this is only an exception; basically all Nurofens contain only one substance.

The difference also lies in the release form; Nurofen has many more of them:

• Film-coated and effervescent tablets with a concentration of 200 to 400 mg of ibuprofen;
• Gel 5% for external use, with a concentration of 50 mg/1g of product;
• Special forms for children: suspension and rectal suppositories. Candles are prescribed from 3 months to 2 years. And suspension from 6 months to 12 years.

Brief description of drugs

Nurofen is a widely used anti-inflammatory and pain reliever whose active ingredient is ibuprofen. The drug is used for:

• Bacterial and viral infections;
• Other inflammatory diseases;
• For the purpose of symptomatic treatment (fever, chills, intoxication, headache, muscle pain, etc.).

Ibuklin is a combination drug that contains ibuprofen and paracetamol. Due to the presence of paracetamol in the drug, it becomes possible to inhibit processes in the central nervous system that stimulate the development of inflammatory reactions.

Ibuklin is used in the same cases as Nurofen.

Comparative characteristics

If you don’t go into details, it may seem that Nurofen and Ibuklin are one and the same. Despite identical indications for use and mechanism of action, these two drugs are somewhat different:

• Taking Nurofen opens up the possibility of combining it with other drugs without excessive drug load on the body;
• In case of severe fever, intoxication, especially in young children, taking ibuclin can reduce persistently high body temperature numbers and eliminate many symptoms of the inflammatory process. Chronic use of this drug is not recommended.

Thus, the difference in the composition of these drugs dictates, although small, but clinically significant differences in their use.

Drug compatibility

In terms of their chemical composition, the drugs are compatible. But under no circumstances should Ibuklin and Nurofen be taken together at one time. This can result in an overdose of ibuprofen and also increase the risk of side effects:

• From the gastrointestinal tract: nausea, vomiting, epigastric pain, ulcers and bleeding;
• Violation of the blood picture: the level of hemoglobin, platelets, and leukocytes decreases;
• Allergic reactions manifest themselves in the form of skin hyperemia and an itchy rash. Less commonly, symptoms of anaphylactic shock may occur;
• Heart failure, arrhythmia, increased heart rate, hypertension;
• Labored breathing.

Therefore, taking the drugs at the same time is not recommended. You can take Nurofen after Ibuklin if at least 6 hours have passed. In other words, the drugs can be taken alternating.

From all of the above, we can conclude that the choice of drug depends on age, form of release, and purpose of its use. If you want to get a good therapeutic effect, it is better to use Ibuklin. If you plan to treat a small child, then it is preferable to buy Nurofen.

Sources:

Vidal : https://www.vidal.ru/drugs/glycine__4429 GRLS : https://grls.rosminzdrav.ru/Grls_View_v2.aspx?routingGuid=80b010cc-df9b-4601-90e4-d8cd11a43524&t=

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Description of drugs

Both drugs belong to the same pharmacological group - non-steroidal anti-inflammatory drugs (NSAIDs). The difference lies in the composition on which the therapeutic effect depends.

Ibuklin is a combined anti-inflammatory drug that has analgesic and antipyretic effects. One tablet contains 2 active ingredients: 400 mg of ibuprofen, 325 mg of paracetamol. Ibuprofen, a derivative of propionic acid, has an analgesic effect by inhibiting the release of pain mediators - prostaglandins. Stimulates the production of natural interferon, increasing the body's defenses in the fight against infection and viruses. Paracetamol affects the thermoregulation center in the brain, helping to normalize body temperature. The combination of these actions reduces the inflammatory process in the body, improving the overall well-being of the patient.

Nurofen is an NSAID with a pronounced analgesic effect. The composition includes the analgesic ibuprofen, and in some forms codeine, a centrally acting antitussive. It differs from Ibuklin in the dosage form produced. It is produced in tablets, syrup, suppositories and gel for external use. All forms are adapted for children based on the dosage of the active substance in one unit and are prescribed by pediatricians. Ibuklin is available only in tablet form; for children there is a variety marked “Junior”. Children's dosage is lower than standard - 125 mg of paracetamol, 100 mg of ibuprofen.

Brief characteristics of drugs

The presented pharmaceuticals are non-steroidal anti-inflammatory drugs that can effectively relieve pain and also reduce fever. It is worth noting that they affect the child’s body in exactly the same way, providing a similar anti-inflammatory, analgesic and antipyretic effect.

Both Ibuprofen and Nurofen contain the same active ingredient – ​​ibuprofen. This component can be quickly absorbed by tissues, and therefore it is observed in the blood within an hour after administration. It can be partially eliminated from the body in just a few hours. But it will take at least a day for complete cleansing.

Due to the fact that the presented medications can have the same effect, consumers still often face the question of what is better for children: Ibuprofen or Nurofen? In order to answer this question, you first need to understand in detail what they contain.

Indications for use

The drugs are used for the treatment of viral and infectious diseases, systemic pathologies, anti-inflammatory processes, colds, and flu. Indications:

• high body temperature;
• pain syndrome of all types: headache, toothache, muscle pain;
• neuralgia;
• local tissue inflammation.

A single dose of both drugs is 200 mg (adults); in children over 6 years of age, the maximum daily dose is 800 mg. Intervals between doses are 6-7 hours.

Ibuklin or Nurofen - which is better?

Both ibuklin and nurofen are used in drug therapy for all conditions accompanied by elevated body temperature, pain, and the accumulation of bacterial toxins in the body. These drugs, like other anti-inflammatory drugs, are especially widely used to eliminate the symptoms of bacterial and viral infections.

From the point of view of the load on the body, liver, and gastric mucosa, the use of Nurofen is more acceptable. The risk of possible complications in the long term, especially if long-term treatment is necessary, is in this case much lower.

Ibuklin is the drug of choice if it is necessary to eliminate fever immediately, at a critical temperature of 39. This is especially important in children of preschool and primary school age, when convulsions may develop against the background of a high temperature.

Comparative characteristics

The difference between Nurofen and Ibuklin is in the number of constituent components. The only option with the same content is Nurofen Long. This option has 500 mg of paracetamol as an additional substance. Ibuklin is only allowed for children over 3 years of age. Nurofen in suppositories is used from 3 months.

1. Compound. More components in Ibuklin.
2. The price is set based on cost; Nurofen has fewer components, so it costs less.
3. Age of patients. Ibuklin is suitable for children of preschool and school age, Nurofen is used from 3 months.
4. Release form. Nurofen is presented in the pharmaceutical market in many variants.
5. Safety. Paracetamol content causes more side effects.

Ibuklin or Nurofen are compatible with each other due to their almost identical composition. You cannot take them at once; the dose will exceed the maximum permissible for the body per dose. Risk of unwanted effects:

• dyspeptic disorders: nausea, vomiting, stool disorders;
• anemia of all types;
• blood clotting disorder;
• increased blood pressure;
• cardiopalmus;
• allergic reactions: urticaria, itching, swelling.

For a course of treatment with both drugs, you must consult a pediatrician. Paracetamol contained in one of them takes longer to be eliminated by the liver and kidneys in childhood, and there is a risk of intoxication. Temperature reduction is allowed at numbers above 38°C. The exception is the appearance of seizures in a child at lower thermometer readings.

Alternating medications should be discussed with your doctor. In case of inflammatory processes of any etiology in a child, it is allowed to give Nurofen in any form, after 4 hours - children's Ibuklin. Check temperature every hour. For effective treatment of adults, it is preferable to use Ibuklin, for children - Nurofen.

Drug interactions

1. Caffeine enhances the analgesic effect of ibuprofen.
2. Antacids and cholestyramine reduce the absorption of the ibuprofen + paracetamol combination.
3. Combination with ethanol and GCS increases the risk of erosive and ulcerative lesions of the gastrointestinal tract.
4. Increases the blood concentration of digoxin, lithium and methotrexate.
5. When this combination is used simultaneously with cyclosporine and gold preparations, nephrotoxicity increases.
6. This combination enhances the hypoglycemic effect of insulin and oral hypoglycemic drugs.
7. Weakens the effects of antihypertensive drugs and diuretics (by inhibiting the synthesis of renal prostaglandins).
8. Myelotoxic drugs contribute to the hematotoxicity of the ibuprofen + paracetamol combination.
9. With simultaneous use of this combination with cefamandole, cefoperazone, cefotetan, valproic acid, plicamycin, the incidence of hypoprothrombinemia increases.
10. Ibuprofen enhances the effect of direct (heparin) and indirect (coumarin and indanedione derivatives) anticoagulants, thrombolytic agents (alteplase, anistreplase, streptokinase, urokinase), antiplatelet agents, colchicine - the risk of developing hemorrhagic complications increases.
11. When used simultaneously with acetylsalicylic acid, ibuprofen reduces its anti-inflammatory and antiplatelet effect (it is possible to increase the incidence of acute coronary insufficiency in patients receiving small doses of acetylsalicylic acid as an antiplatelet agent after starting treatment).

For several years in a row, Nurofen has been ranked first in the ranking of the best-selling over-the-counter drugs in Russia, despite the existence of a whole list of cheaper analogues. This is due to a number of advantages that make Nurofen the drug of choice in childhood (in appropriate forms). Although Ibuklin is not a complete analogue of Nurofen, it is preferred for its combined action and more pronounced effect. Let's compare the pros and cons of both drugs in more detail.

There are contraindications, consult a specialist

Nurofen contains only one active ingredient - ibuprofen

, but in addition to tablets and capsules, it is available in the form of a suspension and even suppositories. This absolute advantage makes it possible to use Nurofen for fever in children starting from 3 months of age. Candles allow you to quickly reduce the temperature of a small child if the use of conventional forms causes vomiting or swallowing is difficult due to a respiratory disease.

The second advantage is the original origin and European production (Great Britain). Unlike cheap analogues, using original drugs is always better

, since when used correctly they 100% guarantee the achievement of the declared effect. And although now most of them are almost the same in composition as Nurofen, due to the quality of the starting materials and the set of excipients, they may be weaker or more likely to cause side effects.

In addition to standard capsules or tablets, Nurofen for adults is available in special versions that have some features:

• increased dosage
• extended duration of action
• accelerated release (capsules with liquid composition)

The name and corresponding feature of the work are given in the table.

Normal enhanced version Enhanced version with accelerated action

By and large, the British drug has only one relative disadvantage - its higher cost per tablet.

This is a combination drug based on two components: ibuprofen (400 mg) + paracetamol (325 mg). This combination makes it possible to more effectively reduce high fever and provides a stronger analgesic effect.

through a combination of ibuprofen and paracetamol.
This has been confirmed by many clinical studies that compared the combined effectiveness of these active ingredients and separately. Indeed, together they potentiate (strengthen) each other’s action. Ibuklin for adults - 10 tablets
However, at the same time, the risk of side effects and load on the liver increases, so Ibuklin should not be taken too often, after alcohol or to combat a hangover.

Ibuklin has only an oral form (tablets for oral administration), but a special “Junior” version has been developed for children. It differs from the usual one in smaller dosages and in the form of dispersible tablets that can be dissolved in water.

Produced in India, therefore, despite the more complex composition, Ibuklin costs almost the same or even slightly cheaper than Nurofen. By the way, in the competitor’s line there is a variant “Nurofen Long”, which, like Ibuklin, uses a combination of ibuprofen with paracetamol, but with a higher dose of the latter (see table).

Active substance

When applied externally, it acts as an anesthetic and relieves inflammation.

The substance is absorbed quite quickly and quickly distributed throughout the body. It is completely excreted through the kidneys within a few hours. The maximum concentration of ibuprofen in the blood is reached after 45 minutes. after taking on an empty stomach or 1-2 hours (depending on the dosage form) after taking with food.

The effect of ibuprofen-based drugs lasts up to eight hours.

Impact on the children's body

Both medications are used as an antipyretic and anti-inflammatory for acute respiratory infections and acute respiratory viral infections, other infectious and inflammatory diseases and for increased body temperature after vaccinations. In addition, these drugs are used to relieve mild or moderate pain: headaches, dental pain, migraines, neuralgia, sore throat and ears, teething, as well as various injuries to muscles, ligaments, bones and tendons. They have no effect on the liver, spleen and digestive system.

If the rules of administration are followed and there are no contraindications, in most cases the treatment proceeds without complications. However, any drug has side effects.

The following problems may occur when taking Nurofen.

• Allergic skin rashes - urticaria, exudative erythema, bronchospasm, Lyell's syndrome, angioedema.
• Deterioration of appetite, dyspepsia, with prolonged use - the occurrence of erosions on the mucous membranes of the gastrointestinal tract.
• Headaches, dizziness, poor sleep, psychomotor agitation.
• Shortness of breath, hypertension, cardiac arrhythmia, sometimes heart failure.
• Cystitis, nephritis, polyuria, impaired renal function.
• Anemia, thrombocytopenia, agranulocytosis, leukopenia.

The use of the drug is allowed in the first and second trimester of pregnancy; in the third trimester, treatment with Nurofen is contraindicated: the drug can cause uterine contractions, which can provoke premature birth. It is better for nursing mothers to take Nurofen for children, but only under the supervision of a doctor.

Ibuprofen may cause the following side effects.

• Nausea, vomiting, diarrhea, anorexia, epigastric discomfort, with long-term use - ulcers and erosions on the mucous membranes of the gastrointestinal tract, sometimes impaired liver function and bleeding from the gastrointestinal tract.
• Headaches, dizziness, decreased visual acuity, poor sleep, psychomotor agitation.
• With long-term treatment - anemia, agranulocytosis, thrombocytopenia, impaired renal function.
• Allergic reactions (can be observed both when taken orally and when used externally): redness, skin rashes, itching and burning, Quincke's edema. Sometimes - aseptic meningitis and bronchospastic syndrome.

What is the difference between Ibuklin and regular ibuprofen?

There are contraindications, use after consulting your doctor

An inexperienced consumer may think that Ibuklin and Ibuprofen are the same medicine. However, a more detailed examination reveals a fundamental difference between the drugs.

Ibuprofen (200 mg/tab)

Let's start with an analytical review of the composition of active substances. Both drugs include ibuprofen

. This chemical compound is a derivative of propionic acid, which has a pronounced antipyretic and anti-inflammatory effect. Ibuprofen has gained recognition due to the fact that it causes fewer side effects compared to many other antipyretics. According to some data, the substance can increase the body's resistance to inflammation by stimulating the immune response.

The presence of a second active ingredient – ​​paracetamol

in Ibuklin, how it differs from Ibuprofen, significantly enhances the antipyretic effect of the drug. This active substance has been used by pharmacologists for more than a century. The advantages of paracetamol are that it does not irritate the mucous membranes of the digestive organs, and also does not disrupt water-salt metabolism. The main thing is not to exceed the dosage, since starting from one gram per day it becomes harmful even to a healthy liver.

One tablet of Ibuclin contains: ibuprofen - 400 mg, paracetamol - 325 mg.

Ibuprofen and paracetamol are compatible with each other chemically, but pharmaceutical science has not yet given a clear answer regarding the complete safety of such a combination. On the one hand, two medicinal substances enhance the therapeutic effect of each other, however, there is a danger of side effects and allergic manifestations.

The variety of release forms is what makes Ibuprofen different. Among them: suspension for oral administration, capsules, gel for external use, rectal suppositories, ointment for external use, tablets in blister packs and film-coated tablets in polymer jars. Ibuklin, in turn, is presented in film-coated tablets.

10 tablets

Both drugs have a comprehensive list of contraindications, including pregnancy and lactation, childhood (up to 12 years for Ibuclin, different depending on the release form for ibuprofen), acute and chronic diseases of various body systems. Consult your doctor and carefully read the instructions before use.

Manufacturer and cost and conclusions

If we touch upon the issue of the difference in price before choosing between Ibuklin and Ibuprofen, then it varies greatly, although in an affordable range. Depending on the form of release, the price of simple ibuprofen ranges from 30 to 150 rubles. Produced by many pharmaceutical companies. companies in Russia. In addition, the tablet forms presented in our pharmacies are produced in Belarus and the Czech Republic. The price of Ibuklin produced in India varies from 150 to 200 rubles.

Thus, when comparing Ibuklin or Ibuprofen - which is better in terms of potency, the first drug “begs to be”, due to the content of two active antipyretic and anti-inflammatory components at once. However, the choice of drug depends on several factors. Among them, we note the patient’s age, predisposition to allergies, the presence of concomitant diseases, etc., so consultation with a specialist is important.